Drug modifies epigenome in aggressive brain tumors

Journal Reference: Lucas A. Salas, Thomas G. Stewart, Bret C. Mobley, Chengwei Peng, Jing Liu, Sudan N. Loganathan, Jialiang Wang, Yanjun Ma, Mitchel S. Berger, Devin Absher, Yang Hu, Paul L. Moots, Brock C. Christensen, Stephen W. Clark. Phase I Study of High-Dose l-Methylfolate in Combination with Temozolomide and Bevacizumab in Recurrent IDH Wild-Type High-Grade … Read more

HIV an infection: Better understanding the reservoir of virus in the body

Journal Reference: Manuel Albanese, Adrian Ruhle, Jennifer Mittermaier, Ernesto Mejías-Pérez, Madeleine Gapp, Andreas Linder, Niklas A. Schmacke, Katharina Hofmann, Alexandru A. Hennrich, David N. Levy, Andreas Humpe, Karl-Klaus Conzelmann, Veit Hornung, Oliver T. Fackler, Oliver T. Keppler. Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4 T cells allows complex functional analyses. … Read more

First model to predict lifetime risk of heart failure

Journal Reference: Sadiya S Khan, Hongyan Ning, Norrina B Allen, Mercedes Carnethon, Clyde W Yancy, Sanjiv J Shah, John T Wilkins, Lu Tian, Donald Lloyd-Jones. Development and Validation of A Long-Term Incident Heart Failure Risk Model. Circulation Research, 2021; DOI: 10.1161/CIRCRESAHA.121.319595 Such a model now exists, thanks to a new Northwestern Medicine study, which derived … Read more

Family dynamics can motivate and prevent talking about health

Journal Reference: Katherine A. Rafferty, Tina A. Coffelt, Nicole Miller. Understanding Criteria that Predict Private Health Information Disclosures between Emerging Adults & Their Parents. Western Journal of Communication, 2021; 1 DOI: 10.1080/10570314.2021.1995622 A new study from Iowa State University finds open dialogue and reciprocal information sharing between parents and emerging adults reduces barriers for talking … Read more

Study finds electric vehicles provide lower carbon emissions through additional channels

Journal Reference: Paul Wolfram, Stephanie Weber, Kenneth Gillingham, Edgar G. Hertwich. Pricing indirect emissions accelerates lowcarbon transition of US light vehicle sector. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-27247-y But a recent study from the Yale School of the Environment published in Nature Communications found that the total indirect emissions from electric vehicles pale in … Read more

Size doesn’t matter: Rock composition determines how deadly a meteorite impact is

Journal Reference: M.J. Pankhurst, C.J. Stevenson, B.C. Coldwell. Meteorites that produce K-feldspar-rich ejecta blankets correspond to mass extinctions. Journal of the Geological Society, 2021; jgs2021-055 DOI: 10.1144/jgs2021-055 The earth has been bombarded by meteorites throughout its long history. Meteorite impacts generate atmospheric dust and cover the Earth’s surface with debris and have long been considered … Read more

Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain

Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain – NovLink Home Mash I Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain We would like to thank the writer of this post for this awesome web content Greater … Read more

Researchers identify biomarker for melancholy, antidepressant response

Journal Reference: Steven D. Targum, Jeffrey Schappi, Athanasia Koutsouris, Runa Bhaumik, Mark H. Rapaport, Natalie Rasgon, Mark M. Rasenick. A novel peripheral biomarker for depression and antidepressant response. Molecular Psychiatry, 2022; DOI: 10.1038/s41380-021-01399-1 Published in a new proof of concept study, researchers led by Mark Rasenick, University of Illinois Chicago distinguished professor of physiology and … Read more

Desert shrubs cranked up water use efficiency to survive a megadrought

Journal Reference: Steven A. Kannenberg, Avery W. Driscoll, Paul Szejner, William R. L. Anderegg, James R. Ehleringer. Rapid increases in shrubland and forest intrinsic water-use efficiency during an ongoing megadrought. Proceedings of the National Academy of Sciences, 2021; 118 (52): e2118052118 DOI: 10.1073/pnas.2118052118 “The Southwest is in a really dry period,” says Steven Kannenberg, postdoctoral … Read more

School closures led to more sleep and better quality of life for adolescents

Journal Reference: Joëlle N. Albrecht, Helene Werner, Noa Rieger, Natacha Widmer, Daniel Janisch, Reto Huber, Oskar G. Jenni. Association of Adolescent Sleep Duration During COVID Pandemic High School Closure – Effects of homeschooling on adolescents’ sleep and health. JAMA Network Open, 2022 DOI: 10.100/jamanetworkopen.2021.42100 The first wave of the Covid-19 pandemic led to the closure … Read more