Once called cellular particles, tiny bubbles may play key role in understanding, treating diseases

Journal Reference: Inna A. Nikonorova, Juan Wang, Alexander L. Cope, Peter E. Tilton, Kaiden M. Power, Jonathon D. Walsh, Jyothi S. Akella, Amber R. Krauchunas, Premal Shah, Maureen M. Barr. Isolation, profiling, and tracking of extracellular vesicle cargo in Caenorhabditis elegans. Current Biology, 2022; DOI: 10.1016/j.cub.2022.03.005 The study, which appears in the journal Current Biology, … Read more

Tuberculosis induces premature cellular aging

Journal Reference: Carly A. Bobak, Abhimanyu, Harini Natarajan, Tanmay Gandhi, Sandra L. Grimm, Tomoki Nishiguchi, Kent Koster, Santiago Carrero Longlax, Qiniso Dlamini, Jacquiline Kahari, Godwin Mtetwa, Jeffrey D. Cirillo, James O’Malley, Jane E. Hill, Cristian Coarfa, Andrew R. DiNardo. Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis. … Read more

Cellular benefits of gene therapy seen decades after treatment

Journal Reference: Natalia Izotova, Christine Rivat, Cristina Baricordi, Elena Blanco, Danilo Pellin, Eleanor Watt, Athina S. Gkazi, Stuart Adams, Kimberly Gilmour, Jinhua Bayford, Claire Booth, H. Bobby Gaspar, Adrian J. Thrasher, Luca Biasco. Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-21834-9 The research … Read more