New evidence of how exercise can counter diabetes damage

Journal Reference: Kareem Abdelsaid, Varadarajan Sudhahar, Ryan A. Harris, Archita Das, Seock‐Won Youn, Yutao Liu, Maggie McMenamin, Yali Hou, David Fulton, Mark W. Hamrick, Yaoliang Tang, Tohru Fukai, Masuko Ushio‐Fukai. Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3. The FASEB Journal, 2022; 36 (3) DOI: 10.1096/fj.202101323R Angiogenesis is … Read more

COVID-19 can directly infect and damage human kidney cells

Journal Reference: Titilola D. Kalejaiye, Rohan Bhattacharya, Morgan A. Burt, Tatianna Travieso, Arinze E. Okafor, Xingrui Mou, Maria Blasi, Samira Musah. SARS-CoV-2 Employ BSG/CD147 and ACE2 Receptors to Directly Infect Human Induced Pluripotent Stem Cell-Derived Kidney Podocytes. Frontiers in Cell and Developmental Biology, 2022; 10 DOI: 10.3389/fcell.2022.855340 The research appeared online April 20 in the … Read more

Mechanism underlying Alzheimer-like damage in the brain of patients with Down Syndrome elucidated

Journal Reference: Mary Elizabeth Curtis, Tiffany Smith, Daohai Yu, Domenico Pratic. Association of Retromer Deficiency and Tau Pathology in Down Syndrome. Annals of Neurology, 2022; DOI: 10.1002/ana.26321 Precisely why Alzheimer-like changes — marked by the build-up of harmful amyloid and tau proteins — occur in the brain in Down syndrome has been unclear. But now, … Read more

Damage to inner ear system predicts fall risk among people with Alzheimer’s disease

Journal Reference: Kevin Biju, Esther Oh, Paul Rosenberg, Qian-Li Xue, Paul Dash, M. Haroon Burhanullah, Yuri Agrawal. Vestibular Function Predicts Balance and Fall Risk in Patients with Alzheimer’s Disease. Journal of Alzheimer’s Disease, 2022; 1 DOI: 10.3233/JAD-215366 Overall, the researchers say, their study found that impairment of the vestibular system was linked to a 50% … Read more

Dementia patients struggle to cope with change because of damage to general intelligence brain networks

Dementia patients struggle to cope with change because of damage to general intelligence brain networks – NovLink Home Mash I Dementia patients struggle to cope with change because of damage to general intelligence brain networks We would love to say thanks to the writer of this post for this awesome web content Dementia patients struggle … Read more

Ridgecrest shows how earthquakes damage Earth’s crust

Journal Reference: Alba M. Rodriguez Padilla, Michael E. Oskin, Christopher W. D. Milliner, Andreas Plesch. Accrual of widespread rock damage from the 2019 Ridgecrest earthquakes. Nature Geoscience, 2022; DOI: 10.1038/s41561-021-00888-w The earthquake zone — which belongs to a network of faults called the Eastern California Shear Zone — is sparsely populated and arid, without much … Read more

Scientists think a peptide could cease, reverse damage to nerve cells

Journal Reference: Zhenyu Chen, Eric Chai, Yongchao Mou, Ricardo H. Roda, Craig Blackstone, Xue-Jun Li. Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons. Brain, 2022; DOI: 10.1093/brain/awab488 The UIC research, published in the clinical neurology and translational neuroscience journal Brain, was led by Xue-Jun Li, the Michael A. Werckle Professor of biomedical sciences … Read more

‘The place does it damage?’ predicts chronic pain outcomes, study shows

Journal Reference: Benedict J. Alter, Nathan P. Anderson, Andrea G. Gillman, Qing Yin, Jong-Hyeon Jeong, Ajay D. Wasan. Hierarchical clustering by patient-reported pain distribution alone identifies distinct chronic pain subgroups differing by pain intensity, quality, and clinical outcomes. PLOS ONE, 2021; 16 (8): e0254862 DOI: 10.1371/journal.pone.0254862 In clinical practice, the bodily distribution of chronic pain … Read more

Research shows scale models effective for predicting storm damage to wood-frame buildings

Journal Reference: Sean Duncan, Daniel Cox, Andre R. Barbosa, Pedro Lomónaco, Hyoungsu Park, Mohammad S. Alam, Caileen Yu. Physical modeling of progressive damage and failure of wood-frame coastal residential structures due to surge and wave forces. Coastal Engineering, 2021; 169: 103959 DOI: 10.1016/j.coastaleng.2021.103959 “We wanted to establish a way to build scaled wood-frame specimens that … Read more

Seismic shockwave pattern may be redirecting earthquake damage

Journal Reference: Daniel T. Trugman, Shanna X. Chu, Victor C. Tsai. Earthquake Source Complexity Controls the Frequency Dependence of Near‐Source Radiation Patterns. Geophysical Research Letters, 2021; 48 (17) DOI: 10.1029/2021GL095022 The study examined data from one of the densest seismic arrays ever deployed and found that earthquakes emit their strongest seismic shockwaves in four opposing … Read more