Lipidomics provides new biomarkers for cardiovascular disease and Type 2 diabetes

Journal Reference: Fabian Eichelmann, Laury Sellem, Clemens Wittenbecher, Susanne Jäger, Olga Kuxhaus, Marcela Prada, Rafael Cuadrat, Kim G. Jackson, Julie A. Lovegrove, Matthias B. Schulze. Deep Lipidomics in Human Plasma – Cardiometabolic Disease Risk and Effect of Dietary Fat Modulation. Circulation, 2022; DOI: 10.1161/CIRCULATIONAHA.121.056805 Cardiovascular disease is the leading cause of death worldwide, accounting for … Read more

Poor diet associated with increased diabetes risk across all gradients of genetic risk

Journal Reference: Jordi Merino, Marta Guasch-Ferré, Jun Li, Wonil Chung, Yang Hu, Baoshan Ma, Yanping Li, Jae H. Kang, Peter Kraft, Liming Liang, Qi Sun, Paul W. Franks, JoAnn E. Manson, Walter C. Willet, Jose C. Florez, Frank B. Hu. Polygenic scores, diet quality, and type 2 diabetes risk: An observational study among 35,759 adults … Read more

New evidence of how exercise can counter diabetes damage

Journal Reference: Kareem Abdelsaid, Varadarajan Sudhahar, Ryan A. Harris, Archita Das, Seock‐Won Youn, Yutao Liu, Maggie McMenamin, Yali Hou, David Fulton, Mark W. Hamrick, Yaoliang Tang, Tohru Fukai, Masuko Ushio‐Fukai. Exercise improves angiogenic function of circulating exosomes in type 2 diabetes: Role of exosomal SOD3. The FASEB Journal, 2022; 36 (3) DOI: 10.1096/fj.202101323R Angiogenesis is … Read more

People with diabetes and cognitive decline may be at higher risk for heart disease

Journal Reference: Tali Cukierman-Yaffe, Hertzel C Gerstein, Jan Basile, M Angelyn Bethel, Ernesto G Cardona-Muñoz, Ignacio Conget, Gilles Dagenais, Edward Franek, Stephanie Hall, Nicolae Hancu, Petr Jansky, Mark Lakshmanan, Fernando Lanas, Lawrence A Leiter, Patricio Lopez-Jaramillo, Valdis Pirags, Nana Pogosova, Jeffrey Probstfield, Purnima Rao-Melacini, Chinthanie Ramasundarahettige, Peter J Raubenheimer, Matthew C Riddle, Lars Rydén, Jonathan … Read more

Exercise during pregnancy reduces the risk of Type-2 Diabetes in offspring

Journal Reference: Joji Kusuyama, Nathan S. Makarewicz, Brent G. Albertson, Ana Barbara Alves-Wagner, Royce H. Conlin, Noah B Prince, Christiano R. R. Alves, Krithika Ramachandran, Chisayo Kozuka, Yang Xiudong, Yang Xia, Michael F. Hirshman, Toshihisa Hatta, Ryoichi Nagatomi, Eva S. Nozik, Laurie J. Goodyear. Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High Fat … Read more

High rate of diabetes, high blood pressure in Puerto Ricans linked to brain changes

Journal Reference: Yi Guan, Seyed Amir Ebrahimzadeh, Chia-hsin Cheng, Weifan Chen, Tiffany Leung, Sherman Bigornia, Natalia Palacios, Mahdi O. Garelnabi, Tammy Scott, Rafeeque Bhadelia, Katherine L. Tucker, Bang-Bon Koo. Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology, 2022; 10.1212/WNL.0000000000200120 DOI: 10.1212/WNL.0000000000200120 “This high … Read more

Origins of diabetes may be different in men and women

Journal Reference: Kerri Z. Delaney, Sylvia Santosa. Sex differences in regional adipose tissue depots pose different threats for the development of Type 2 diabetes in males and females. Obesity Reviews, 2022; 23 (3) DOI: 10.1111/obr.13393 Although the disease is common, there is still much research left to be done to fully understand it. For instance, … Read more

Innovative AI technology aids personalized care for diabetes patients needing complex drug treatment

Journal Reference: Shinji Tarumi, Wataru Takeuchi, Rong Qi, Xia Ning, Laura Ruppert, Hideyuki Ban, Daniel H. Robertson, Titus K. Schleyer, Kensaku Kawamoto. Predicting pharmacotherapeutic outcomes for type 2 diabetes: An evaluation of three approaches to leveraging electronic health record data from multiple sources. Journal of Biomedical Informatics, 2022; 104001 DOI: 10.1016/j.jbi.2022.104001 For this smaller group … Read more

Harnessing the power of AI to advance knowledge of Type 1 diabetes

Journal Reference: Erin M. Tallon, Maria J. Redondo, Chi-Ren Shyu, Danlu Liu, Katrina Boles, Mark A. Clements. Contrast Pattern Mining With the T1D Exchange Clinic Registry Reveals Complex Phenotypic Factors and Comorbidity Patterns Associated With Familial Versus Sporadic Type 1 Diabetes. Diabetes Care, 2022; 45 (3): e56 DOI: 10.2337/dc21-2239 In the study, the team analyzed … Read more

People with diabetes who eat less processed food at night may live longer

Journal Reference: Wenbo Jiang, Qingrao Song, Jia Zhang, Yunyan Chen, Hongyan Jiang, Yujia Long, Ying Li, Tianshu Han, Hongru Sun, Wei Wei. The Association of Consumption Time for Food with Cardiovascular Disease and All-Cause Mortality Among Diabetes Patients. The Journal of Clinical Endocrinology & Metabolism, 2022 DOI: 10.1210/clinem/dgac069 Mealtimes should be in line with the … Read more