Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain

Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain – NovLink Home Mash I Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain We would like to thank the writer of this post for this awesome web content Greater … Read more

Gene therapy strategy found effective in mouse model of hereditary disease TSC

Journal Reference: Pike-See Cheah, Shilpa Prabhakar, David Yellen, Roberta L. Beauchamp, Xuan Zhang, Shingo Kasamatsu, Roderick T. Bronson, Elizabeth A. Thiele, David J. Kwiatkowski, Anat Stemmer-Rachamimov, Bence György, King-Hwa Ling, Masao Kaneki, Bakhos A. Tannous, Vijaya Ramesh, Casey A. Maguire, Xandra O. Breakefield. Gene therapy for tuberous sclerosis complex type 2 in a mouse model … Read more

Disarming a blood-clotting protein prevents gum disease in mice

Journal Reference: Lakmali M. Silva, Andrew D. Doyle, Teresa Greenwell-Wild, Nicolas Dutzan, Collin L. Tran, Loreto Abusleme, Lih Jiin Juang, Jerry Leung, Elizabeth M. Chun, Andrew G. Lum, Cary S. Agler, Carlos E. Zuazo, Megan Sibree, Priyam Jani, Vardit Kram, Daniel Martin, Kevin Moss, Michail S. Lionakis, Francis J. Castellino, Christian J. Kastrup, Matthew J. … Read more

Taking high-dose vitamin D supplements for five years did not affect the incidence of cardiovascular disease or cancer

Taking high-dose vitamin D supplements for five years did not affect the incidence of cardiovascular disease or cancer – NovLink Home Mash B Taking high-dose vitamin D supplements for five years did not affect the incidence of cardiovascular disease or cancer We wish to give thanks to the writer of this short article for this … Read more

Findings open the way to more precise diagnoses and treatments of Alzheimer’s disease

Journal Reference: Chae Kim, Tracy Haldiman, Sang-Gyun Kang, Lenka Hromadkova, Zhuang Zhuang Han, Wei Chen, Frances Lissemore, Alan Lerner, Rohan de Silva, Mark L. Cohen, David Westaway, Jiri G. Safar. Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer’s disease. Science Translational Medicine, 2022; 14 (626) DOI: 10.1126/scitranslmed.abg0253 The researchers found a … Read more

One autoimmune disease could lead to another

Journal Reference: V. Michael Holers, Francisco G. La Rosa, Nirmal K. Banda. A Potential New Mouse Model of Axial Spondyloarthritis Involving the Complement System. Immune Network, 2021; 21 (6) DOI: 10.4110/in.2021.21.e45 The scientists serendipitously found that mice with antibody-induced rheumatoid arthritis in their joints went on to develop spinal lesions similar to those in axial … Read more

Experimental gene therapy reverses sickle cell disease for years

Journal Reference: Julie Kanter, Mark C. Walters, Lakshmanan Krishnamurti, Markus Y. Mapara, Janet L. Kwiatkowski, Stacey Rifkin-Zenenberg, Banu Aygun, Kimberly A. Kasow, Francis J. Pierciey, Melissa Bonner, Alex Miller, Xinyan Zhang, Jessie Lynch, Dennis Kim, Jean-Antoine Ribeil, Mohammed Asmal, Sunita Goyal, Alexis A. Thompson, John F. Tisdale. Biologic and Clinical Efficacy of LentiGlobin for Sickle … Read more

For cardiovascular disease sufferers, more physical activity may be higher, research suggests

For cardiovascular disease sufferers, more physical activity may be higher, research suggests – NovLink Home Mash B For cardiovascular disease sufferers, more physical activity may be higher, research suggests We would like to thank the writer of this write-up for this incredible web content For cardiovascular disease sufferers, more physical activity may be higher, research … Read more

Switching on a key cancer gene could provide first curative treatment for heart disease

Journal Reference: Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan, Catherine H. Wilson. Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity. Nature … Read more

Targeting the brain’s immune cells may help prevent or treat Alzheimer’s disease

Journal Reference: Faten A. Sayed, Lay Kodama, Li Fan, Gillian K. Carling, Joe C. Udeochu, David Le, Qingyun Li, Lu Zhou, Man Ying Wong, Rose Horowitz, Pearly Ye, Hansruedi Mathys, Minghui Wang, Xiang Niu, Linas Mazutis, Xueqiao Jiang, Xueting Wang, Fuying Gao, Matthew Brendel, Maria Telpoukhovskaia, Tara E. Tracy, Georgia Frost, Yungui Zhou, Yaqiao Li, … Read more

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