Neolithic made us taller and more intelligent but more prone to heart disease

Journal Reference: Yunus Kuijpers, Jorge Domínguez-Andrés, Olivier B. Bakker, Manoj Kumar Gupta, Martin Grasshoff, Cheng-Jian Xu, Leo A.B. Joosten, Jaume Bertranpetit, Mihai G. Netea, Yang Li. Evolutionary Trajectories of Complex Traits in European Populations of Modern Humans. Frontiers in Genetics, 2022; 13 DOI: 10.3389/fgene.2022.833190 Just like plants, animals and other organisms, humans are dynamic organisms … Read more

Social determinants of health affect care for people with congenital heart disease

Journal Reference: Keila N. Lopez, Carissa Baker‐Smith, Glenn Flores, Michelle Gurvitz, Tara Karamlou, Flora Nunez Gallegos, Sara Pasquali, Angira Patel, Jennifer K. Peterson, Jason L. Salemi, Clyde Yancy, Shabnam Peyvandi. Addressing Social Determinants of Health and Mitigating Health Disparities Across the Lifespan in Congenital Heart Disease: A Scientific Statement From the American Heart Association. Journal … Read more

HIV drug stabilizes disease progression in metastatic colorectal cancer

Journal Reference: Mihir Rajurkar, Aparna R. Parikh, Alexander Solovyov, Eunae You, Anupriya S. Kulkarni, Chong Chu, Katherine H. Xu, Christopher Jaicks, Martin S. Taylor, Connie Wu, Katherine A. Alexander, Charly R. Good, Annamaria Szabolcs, Stefanie Gerstberger, Antuan V. Tran, Nova Xu, Richard Y. Ebright, Emily E. Van Seventer, Kevin D. Vo, Eric C. Tai, Chenyue … Read more

Combination of biomarkers can identify common cognitive disease

Journal Reference: Petronella Kettunen, Maria Bjerke, Carl Eckerström, Michael Jonsson, Henrik Zetterberg, Kaj Blennow, Johan Svensson, Anders Wallin. Blood‐brain barrier dysfunction and reduced cerebrospinal fluid levels of soluble amyloid precursor protein‐β in patients with subcortical small‐vessel disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022; 14 (1) DOI: 10.1002/dad2.12296 Subcortical small-vessel disease is one … Read more

Novel nuclear microRNA is being developed for the treatment of cardiovascular disease

Journal Reference: Pia Laitinen, Mari-Anna Väänänen, Ida-Liisa Kolari, Petri I. Mäkinen, Minna U. Kaikkonen, Marc S. Weinberg, Kevin V. Morris, Paula Korhonen, Tarja Malm, Seppo Ylä-Herttuala, Thomas C. Roberts, Mikko P. Turunen, Tiia A. Turunen. Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia. PLOS ONE, 2022; 17 (3): e0265948 DOI: 10.1371/journal.pone.0265948 MicroRNAs are small … Read more

Plant-based omega-3s may boost heart well being, reduce risk of heart disease

Journal Reference: Aleix Sala-Vila, Jennifer Fleming, Penny Kris-Etherton, Emilio Ros. Impact of Alpha-linolenic Acid, the Vegetable Omega-3 Fatty Acid, on Cardiovascular Disease and Cognition. Advances in Nutrition, 2022; DOI: 10.1093/advances/nmac016 In a comprehensive literature review, the researchers found that consuming ALA that is found in plant-based foods like walnuts and flaxseeds was associated with a … Read more

Lipid and glucose levels at age 35 associated with Alzheimer’s disease

Journal Reference: Xiaoling Zhang, Tong Tong, Andrew Chang, Ting Fang Alvin Ang, Qiushan Tao, Sanford Auerbach, Sherral Devine, Wei Qiao Qiu, Jesse Mez, Joseph Massaro, Kathryn L. Lunetta, Rhoda Au, Lindsay A. Farrer. Midlife lipid and glucose levels are associated with Alzheimer’s disease. Alzheimer’s & Dementia, 2022; DOI: 10.1002/alz.12641 “While our findings confirm other studies … Read more

Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model

Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model – NovLink Home Mash I Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model We want to thank the author of this post for this incredible web content Researchers discover intake of FDA-approved drug modulates disease progression in … Read more

Link between high cholesterol and heart disease ‘inconsistent’, new study finds

Journal Reference: Paula Byrne, Maryanne Demasi, Mark Jones, Susan M. Smith, Kirsty K. O’Brien, Robert DuBroff. Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment. JAMA Internal Medicine, 2022; DOI: 10.1001/jamainternmed.2022.0134 Published in JAMA Internal Medicine, the research questions the efficacy of statins when prescribed with the aim … Read more

Plasma biomarker screening could improve accuracy, health equity in Alzheimer’s disease diagnosis

Journal Reference: Joseph S. Reddy, Jiangli Jin, Sarah J. Lincoln, Charlotte C.G. Ho, Julia E. Crook, Xue Wang, Kimberly G. Malphrus, Thuy Nguyen, Nikoleta Tamvaka, Maria T. Greig-Custo, John A. Lucas, Neill R. Graff-Radford, Nilüfer Ertekin-Taner, Minerva M. Carrasquillo. Transcript levels in plasma contribute substantial predictive value as potential Alzheimer’s disease biomarkers in African Americans. … Read more