Recreational marijuana access reduces demand for prescription drugs

Journal Reference: Shyam Raman, Ashley Bradford. Recreational cannabis legalizations associated with reductions in prescription drug utilization among Medicaid enrollees. Health Economics, 2022; DOI: 10.1002/hec.4519 When states legalize marijuana, the volume of prescriptions within the drug classes that align with the medical indications for pain, depression, anxiety, sleep, psychosis and seizures significantly decline, the researchers found. … Read more

Research could enable assembly line synthesis of prevalent amine-containing drugs

Journal Reference: Siraj Z. Ali, Brenna G. Budaitis, Devon F. A. Fontaine, Andria L. Pace, Jacob A. Garwin, M. Christina White. Allylic C–H amination cross-coupling furnishes tertiary amines by electrophilic metal catalysis. Science, 2022; 376 (6590): 276 DOI: 10.1126/science.abn8382 Open the household medicine cabinet and you will likely find organic derivatives of ammonia, called amines. … Read more

Drugs, guns and murder – how the ‘untouchable’ Kinahan Cartel joined the ranks of the world’s most dangerous narco-terrorism gangs – Reuters News in France and abroad

Drugs guns and murder how the untouchable Kinahan Cartel

The IRISH Kinahan Cartel is now rated as being as dangerous as some of the deadliest narco-terrorist gangs in the world. A senior US government Treasury Department official spoke at a historic press conference at Dublin City Hall yesterday, Cartel leader Daniel Kinahan Mexico’s murderous criminal group Los Zetas Investigator Gregory Gatjanis explained how Daniel … Read more

Genetic ‘hotspots’ that speed up and slow down brain aging could provide new targets for Alzheimer’s drugs

Genetic ‘hotspots’ that speed up and slow down brain aging could provide new targets for Alzheimer’s drugs – NovLink Home Mash E Genetic ‘hotspots’ that speed up and slow down brain aging could provide new targets for Alzheimer’s drugs We want to say thanks to the writer of this short article for this incredible material … Read more

Time to shift research focus from ‘bikini drugs’ to what is really ailing women

Journal Reference: Laura Hallam, Amy Vassallo, Ana-Catarina Pinho-Gomes, Cheryl Carcel, Mark Woodward. Does Journal Content in the Field of Women’s Health Represent Women’s Burden of Disease? A Review of Publications in 2010 and 2020. Journal of Women’s Health, 2022; DOI: 10.1089/jwh.2021.0425 Despite growing awareness of differences in how women experience medical conditions and the impact … Read more

Twisted vibrations enable quality control for chiral drugs and supplements

Journal Reference: Choi, W.J., Yano, K., Cha, M. et al. Chiral phonons in microcrystals and nanofibrils of biomolecules. Nat. Photon, 2022 DOI: 10.1038/s41566-022-00969-1 The researchers hope that the technique could also help diagnose harmful accumulations of twisted molecules in the body, including bladder stones, insulin fibrils and amyloid aggregations such as the plaques that appear … Read more

Senolytic drugs boost key protective protein

Journal Reference: Yi Zhu, Larissa G.P. Langhi Prata, Erin O. Wissler Gerdes, Jair Machado Espindola Netto, Tamar Pirtskhalava, Nino Giorgadze, Utkarsh Tripathi, Christina L. Inman, Kurt O. Johnson, Ailing Xue, Allyson K. Palmer, Tingjun Chen, Kalli Schaefer, Jamie N. Justice, Anoop M. Nambiar, Nicolas Musi, Stephen B. Kritchevsky, Jun Chen, Sundeep Khosla, Diana Jurk, Marissa … Read more

Discovery of novel brain fear mechanisms offers target for anxiety-reducing drugs

Journal Reference: Elena Paci, Charlotte Lawrenson, Jasmine Pickford, Robert AR Drake, Bridget M Lumb, Richard Apps. Cerebellar modulation of memory encoding in the periaqueductal grey and fear behaviour. eLife, 2022; 11 DOI: 10.7554/eLife.76278 Existing anxiety-reducing drugs are not always effective for all patients and often have unwanted side effects. Understanding the brain networks and mechanisms … Read more

New discovery may help reduce side effects of multiple sclerosis drugs

Journal Reference: Shian Liu, Navid Paknejad, Lan Zhu, Yasuyuki Kihara, Manisha Ray, Jerold Chun, Wei Liu, Richard K. Hite, Xin-Yun Huang. Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28417-2 The study, published Feb. 8 in Nature Communications, details the precise molecular structure of the … Read more

Contraband prison guard ‘trains as a hairdresser’ after he was caught delivering drugs as cops searched his home – Reuters

Contraband prison guard trains as a hairdresser after he was

A DRUG-dealing prison guard started ‘hairdresser training’ after she was arrested by cops who searched her home. Shamed Rio Moran, 31, was recruited by criminals to aid their elaborate plot to smuggle contraband into HMP Doncaster. Prison warden Rio Moran smuggled phones and drugs into inmates at HMP Doncaster1 credit The 31-year-old tried her hand … Read more