Scientists identify novel approach to preventing seizures

Journal Reference: Chris Greene, Nicole Hanley, Cristina R. Reschke, Avril Reddy, Maarja A. Mäe, Ruairi Connolly, Claire Behan, Eoin O’Keeffe, Isobel Bolger, Natalie Hudson, Conor Delaney, Michael A. Farrell, Donncha F. O’Brien, Jane Cryan, Francesca M. Brett, Alan Beausang, Christer Betsholtz, David C. Henshall, Colin P. Doherty, Matthew Campbell. Microvascular stabilization via blood-brain barrier regulation prevents … Read more

Researchers identify a new treatment for metabolic syndrome

Journal Reference: Ila Mishra, Wei Rose Xie, Juan C. Bournat, Yang He, Chunmei Wang, Elizabeth Sabath Silva, Hailan Liu, Zhiqiang Ku, Yinghua Chen, Bernadette O. Erokwu, Peilin Jia, Zhongming Zhao, Zhiqiang An, Chris A. Flask, Yanlin He, Yong Xu, Atul R. Chopra. Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor. Cell Metabolism, … Read more

Researchers identify an immunotherapy target to combat glioblastomas

Journal Reference: Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, William F. Flynn, Ruli Gao, David S. Baskin, Kumar Pichumani, Omkar B. Ijare, Stephanie L. Wood, Suzanne Z. Powell, David L. Haviland, Brittany C. Parker Kerrigan, Frederick F. Lang, Sujit S. Prabhu, Kristin M. Huntoon, Wen Jiang, Betty Y. S. Kim, Joshy George, Kyuson Yun. … Read more

Researchers identify neuronal mechanisms that control food cravings during pregnancy

Journal Reference: Haddad-Tóvolli, R.; Ramírez, S.; Muñoz-Moreno, E.; Milà-Guasch, M.; Miquel-Rio, L.; Pozo, M.; Chivite, I.; Altirriba, J.; Obri, A.; Gómez-Valadés, A.; Toledo, M.; Eyre, E.; Bortolozzi, A.; Valjent, E.; Soria, G.; Claret, M. Food craving-like episodes during pregnancy are mediated by accumbal dopaminergic circuits. Nature Metabolism, 2022 DOI: 10.1038/s42255-022-00557-1 “There are many myths and … Read more

Combination of biomarkers can identify common cognitive disease

Journal Reference: Petronella Kettunen, Maria Bjerke, Carl Eckerström, Michael Jonsson, Henrik Zetterberg, Kaj Blennow, Johan Svensson, Anders Wallin. Blood‐brain barrier dysfunction and reduced cerebrospinal fluid levels of soluble amyloid precursor protein‐β in patients with subcortical small‐vessel disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022; 14 (1) DOI: 10.1002/dad2.12296 Subcortical small-vessel disease is one … Read more

Researchers identify key complex for ribosome generation

Journal Reference: Chunyang Ni, Daniel A. Schmitz, Jeon Lee, Krzysztof Pawłowski, Jun Wu, Michael Buszczak. Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly. Cell Reports, 2022; 38 (13): 110597 DOI: 10.1016/j.celrep.2022.110597 “Ribosomes are fundamental for life, but we’ve had an incomplete understanding of how they’re put together … Read more

Neuroscientists identify mechanism for long term memory storage

Journal Reference: Snehajyoti Chatterjee, Ethan Bahl, Utsav Mukherjee, Emily N. Walsh, Mahesh Shivarama Shetty, Amy L. Yan, Yann Vanrobaeys, Joseph D. Lederman, K. Peter Giese, Jacob Michaelson, Ted Abel. Endoplasmic reticulum chaperone genes encode effectors of long-term memory. Science Advances, 2022; 8 (12) DOI: 10.1126/sciadv.abm6063 While working to understand how memories are formed and stored … Read more

Scientists identify overgrowth of key brain structure in babies who later develop autism

Journal Reference: Mark D. Shen, Meghan R. Swanson, Jason J. Wolff, Jed T. Elison, Jessica B. Girault, Sun Hyung Kim, Rachel G. Smith, Michael M. Graves, Leigh Anne H. Weisenfeld, Lisa Flake, Leigh MacIntyre, Julia L. Gross, Catherine A. Burrows, Vladimir S. Fonov, D. Louis Collins, Alan C. Evans, Guido Gerig, Robert C. McKinstry, Juhi … Read more

Scientists identify possible new treatment for COVID-19

Journal Reference: A.G. Ibrahim, A. Ciullo, C. Li, G. Garcia, K. Peck, K. Miyamoto, V. Arumugaswami, E. Marbán. Engineered extracellular vesicles antagonize SARS-CoV-2 infection by inhibiting mTOR signaling. Biomaterials and Biosystems, 2022; 6: 100042 DOI: 10.1016/j.bbiosy.2022.100042 Scientists found the substance stopped SARS-CoV-2, the virus that causes COVID-19, from reproducing itself and also protected infected cells … Read more

Genetic mutation may identify women with difficulty producing breast milk

Journal Reference: Desirae Chandran, Alexandra Confair, Kaitlyn Warren, Yuka Imamura Kawasawa, Steven D. Hicks. Maternal Variants in the MFGE8 Gene are Associated with Perceived Breast Milk Supply. Breastfeeding Medicine, 2021; DOI: 10.1089/bfm.2021.0216 “The World Health Organization, the American Academy of Pediatrics and the American College of Obstetricians and Gynecologists recommend exclusive breastfeeding for at least … Read more