Pain in the neck? New surgical method could be game-changing

Journal Reference: Maohua Lin, Stephen Z. Shapiro, Erik D. Engeberg, Chi-Tay Tsai, Frank D. Vrionis. Finite Element Analysis of the Effect of Dynamic Plating on Two-Level Anterior Cervical Discectomy Fusion Biomechanics. World Neurosurgery, 2022; DOI: 10.1016/j.wneu.2022.02.032 The use of cages for ACDF are important postoperatively to the alignment of the cervical spine and to maintain … Read more

Stem cell-based biomaterial can help regenerate tissue associated with low back pain and spinal issues

Journal Reference: Takashi Kamatani, Hiroki Hagizawa, Seido Yarimitsu, Miho Morioka, Saeko Koyamatsu, Michihiko Sugimoto, Joe Kodama, Junko Yamane, Hiroyuki Ishiguro, Shigeyuki Shichino, Kuniya Abe, Wataru Fujibuchi, Hiromichi Fujie, Takashi Kaito, Noriyuki Tsumaki. Human iPS cell-derived cartilaginous tissue spatially and functionally replaces nucleus pulposus. Biomaterials, 2022; 284: 121491 DOI: 10.1016/j.biomaterials.2022.121491 It is believed that IVD degeneration … Read more

Men and women process pain signals differently

Journal Reference: Annemarie Dedek, Jian Xu, Louis-Étienne Lorenzo, Antoine G Godin, Chaya M Kandegedara, Geneviève Glavina, Jeffrey A Landrigan, Paul J Lombroso, Yves De Koninck, Eve C Tsai, Michael E Hildebrand. Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain. Brain, 2022; DOI: 10.1093/brain/awab408 Although it has … Read more

Style, temperature and pain sensations are neurologically linked

Journal Reference: Jinrong Li, Md Sams Sazzad Ali, Christian H. Lemon. TRPV1-Lineage Somatosensory Fibers Communicate with Taste Neurons in the Mouse Parabrachial Nucleus. The Journal of Neuroscience, 2022; 42 (9): 1719 DOI: 10.1523/JNEUROSCI.0927-21.2021 “The spicy hot sensation you get from a chili pepper is actually a pain sensation…this follows activation of pain-related fibers that innervate … Read more

Researchers map human sensory neurons, pursue chronic pain cure

Journal Reference: Diana Tavares-Ferreira, Stephanie Shiers, Pradipta R. Ray, Andi Wangzhou, Vivekanand Jeevakumar, Ishwarya Sankaranarayanan, Anna M. Cervantes, Jeffrey C. Reese, Alexander Chamessian, Bryan A. Copits, Patrick M. Dougherty, Robert W. Gereau, Michael D. Burton, Gregory Dussor, Theodore J. Price. Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors. Science Translational Medicine, … Read more

How chronic pain arises

Journal Reference: Christian Litke, Anna M. Hagenston, Ann-Kristin Kenkel, Eszter Paldy, Jianning Lu, Rohini Kuner, Daniela Mauceri. Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in mice. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28357-x “Normal, acute physiological pain prevents tissue damage and, in the case of injury, resolves with healing. Chronic pathological … Read more

Mindfulness therapy reduces opioid misuse and chronic pain in primary care, according to new research

Mindfulness therapy reduces opioid misuse and chronic pain in primary care, according to new research – NovLink Home Mash Q Mindfulness therapy reduces opioid misuse and chronic pain in primary care, according to new research We would like to thank the author of this short article for this outstanding web content Mindfulness therapy reduces opioid … Read more

New clues in the brain linking pain and food

Journal Reference: Yezhe Lin, Ivan De Araujo, Gelsina Stanley, Dana Small, Paul Geha. Chronic pain precedes disrupted eating behavior in low-back pain patients. PLOS ONE, 2022; 17 (2): e0263527 DOI: 10.1371/journal.pone.0263527 Finding pleasure in food comes from how our brain responds to what we are eating. In this study researchers were looking at the brain’s … Read more

Virtual reality as pain aid: Reducing dressing change pain in pediatric burn patients

Journal Reference: Henry Xiang, Jiabin Shen, Krista K. Wheeler, Jeremy Patterson, Kimberly Lever, Megan Armstrong, Junxin Shi, Rajan K. Thakkar, Jonathan I. Groner, Dana Noffsinger, Sheila A. Giles, Renata B. Fabia. Efficacy of Smartphone Active and Passive Virtual Reality Distraction vs Standard Care on Burn Pain Among Pediatric Patients. JAMA Network Open, 2021; 4 (6): … Read more

Smart sensor equipped chair may help office workers reduce their back pain woes

Journal Reference: Ziheng Wang, Keizo Sato, Saida Salima Nawrin, Namareq Salah Widatalla, Yoshitaka Kimura, Ryoichi Nagatomi. Low Back Pain Exacerbation Is Predictable Through Motif Identification in Center of Pressure Time Series Recorded During Dynamic Sitting. Frontiers in Physiology, 2021; 12 DOI: 10.3389/fphys.2021.696077 Now, researchers at Tohoku University have developed a new prediction method that employs … Read more