Transmission - Debatepost

Helping prevent transmission of HIV from mother to child during breastfeeding

April 25, 2022 by Tony Grantly

Journal Reference: Allison S. Thomas, Carolyn Coote, Yvetane Moreau, John E. Isaac, Alexander C. Ewing, Athena P. Kourtis, Manish Sagar. Antibody-dependent cellular cytotoxicity (ADCC) responses along with ADCC susceptibility influence HIV-1 mother to child transmission. JCI Insight, 2022; DOI: 10.1172/jci.insight.159435 Researchers evaluated ADCC and neutralizing antibody (nAb) properties in pre-transmission plasma from HIV-1 exposed infants … Read more

Body’s response to different strains of tuberculosis could affect transmission

April 17, 2022 by Tony Grantly

Journal Reference: Arianne Lovey, Sheetal Verma, Vaishnavi Kaipilyawar, Rodrigo Ribeiro-Rodrigues, Seema Husain, Moises Palaci, Reynaldo Dietze, Shuyi Ma, Robert D. Morrison, David. R. Sherman, Jerrold J. Ellner, Padmini Salgame. Early alveolar macrophage response and IL-1R-dependent T cell priming determine transmissibility of Mycobacterium tuberculosis strains. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28506-2 The findings, published in … Read more

Inhalable ‘aerogel’ triggers immunity to COVID-19 in mice, may block transmission

March 19, 2022 by Tony Grantly

Journal Reference: Atip Lawanprasert, Andrew W. Simonson, Sarah E. Sumner, McKayla J. Nicol, Sopida Pimcharoen, Girish S. Kirimanjeswara, Scott H. Medina. Inhalable SARS-CoV-2 Mimetic Particles Induce Pleiotropic Antigen Presentation. Biomacromolecules, 2022; 23 (3): 1158 DOI: 10.1021/acs.biomac.1c01447 “There are many potential advantages of an inhalable formulation compared to an injectable vaccine,” said Atip Lawanprasert, graduate student … Read more

Mother to child transmission of COVID-19 an infection, possible but uncommon, study finds

March 17, 2022 by Tony Grantly

Journal References: John Allotey, Shaunak Chatterjee, Tania Kew, Andrea Gaetano, Elena Stallings, Silvia Fernández-García, Magnus Yap, Jameela Sheikh, Heidi Lawson, Dyuti Coomar, Anushka Dixit, Dengyi Zhou, Rishab Balaji, Megan Littmoden, Yasmin King, Luke Debenham, Anna Clavé Llavall, Kehkashan Ansari, Gurimaan Sandhu, Adeolu Banjoko, Kate Walker, Keelin O’Donoghue, Madelon van Wely, Elizabeth van Leeuwen, Elena Kostova, … Read more

Exploring ancient tuberculosis transmission chains

March 12, 2022 by Tony Grantly

Journal Reference: Åshild J. Vågene, Tanvi P. Honap, Kelly M. Harkins, Michael S. Rosenberg, Karen Giffin, Felipe Cárdenas-Arroyo, Laura Paloma Leguizamón, Judith Arnett, Jane E. Buikstra, Alexander Herbig, Johannes Krause, Anne C. Stone, Kirsten I. Bos. Geographically dispersed zoonotic tuberculosis in pre-contact South American human populations. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28562-8 Analyses of … Read more

COVID-19 study in Australia confirms low transmission in educational settings

February 16, 2022 by Tony Grantly

Journal Reference: Kristine Macartney, Helen E Quinn, Alexis J Pillsbury, Archana Koirala, Lucy Deng, Noni Winkler, Anthea L Katelaris, Matthew V N O’Sullivan, Craig Dalton, Nicholas Wood, D Brogan, C Glover, N Dinsmore, A Dunn, A Jadhav, R Joyce, R Kandasamy, K Meredith, L Pelayo, L Rost, G Saravanos, S Bag, S Corbett, M Staff, … Read more