‘Keto’ molecule may be useful in preventing and treating colorectal most cancers, study suggests

Journal Reference: Oxana Dmitrieva-Posocco, Andrea C. Wong, Patrick Lundgren, Aleksandra M. Golos, Hélène C. Descamps, Lenka Dohnalová, Zvi Cramer, Yuhua Tian, Brian Yueh, Onur Eskiocak, Gabor Egervari, Yemin Lan, Jinping Liu, Jiaxin Fan, Jihee Kim, Bhoomi Madhu, Kai Markus Schneider, Svetlana Khoziainova, Natalia Andreeva, Qiaohong Wang, Ning Li, Emma E. Furth, Will Bailis, Judith R. … Read more

New approach against chronic irritation: Treating mice with so-called ‘nanobodies’

Journal Reference: Damien Bertheloot, Carlos WS Wanderley, Ayda H Schneider, Lisa DJ Schiffelers, Jennifer D Wuerth, Jan MP Tödtmann, Salie Maasewerd, Ibrahim Hawwari, Fraser Duthie, Cornelia Rohland, Lucas S Ribeiro, Lea‐Marie Jenster, Nathalia Rosero, Yonas M Tesfamariam, Fernando Q Cunha, Florian I Schmidt, Bernardo S Franklin. Nanobodies dismantle post‐pyroptotic ASC specks and counteract inflammation in vivo. … Read more

Primary care medical home found to be more effective than usual care in treating patients with serious mental illness

Primary care medical home found to be more effective than usual care in treating patients with serious mental illness – NovLink Home Mash H Primary care medical home found to be more effective than usual care in treating patients with serious mental illness We would love to give thanks to the author of this post … Read more

An approach to treating a severe congenital myopathy

Journal Reference: Alexis Ruiz, Sofia Benucci, Urs Duthaler, Christoph Bachmann, Martina Franchini, Faiza Noreen, Laura Pietrangelo, Feliciano Protasi, Susan Treves, Francesco Zorzato. Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors. eLife, 2022; 11 DOI: 10.7554/eLife.73718 Professor Susan Treves remembers seeing one child affected by the … Read more

Once called cellular particles, tiny bubbles may play key role in understanding, treating diseases

Journal Reference: Inna A. Nikonorova, Juan Wang, Alexander L. Cope, Peter E. Tilton, Kaiden M. Power, Jonathon D. Walsh, Jyothi S. Akella, Amber R. Krauchunas, Premal Shah, Maureen M. Barr. Isolation, profiling, and tracking of extracellular vesicle cargo in Caenorhabditis elegans. Current Biology, 2022; DOI: 10.1016/j.cub.2022.03.005 The study, which appears in the journal Current Biology, … Read more

Higher dose antibiotic shown safe in TB patients likely more effective in treating deadliest form of TB

Journal Reference: Camilo A. Ruiz-Bedoya, Filipa Mota, Elizabeth W. Tucker, Farina J. Mahmud, Maria I. Reyes-Mantilla, Clara Erice, Melissa Bahr, Kelly Flavahan, Patricia de Jesus, John Kim, Catherine A. Foss, Charles A. Peloquin, Dima A. Hammoud, Alvaro A. Ordonez, Carlos A. Pardo, Sanjay K. Jain. High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in … Read more

Treating cancer with light-sensitive nanoscale biomaterials

Journal Reference: Behzad Nasseri, Effat Alizadeh, Farhad Bani, Soodabeh Davaran, Abolfazl Akbarzadeh, Navid Rabiee, Ali Bahadori, Mojtaba Ziaei, Mojtaba Bagherzadeh, Mohammad Reza Saeb, Masoud Mozafari, Michael R. Hamblin. Nanomaterials for photothermal and photodynamic cancer therapy. Applied Physics Reviews, 2022; 9 (1): 011317 DOI: 10.1063/5.0047672 One technique, known as photothermal therapy (PTT), converts laser light into … Read more

Patient-centered approach to treating obesity

Journal Reference: Michelle I. Cardel, Faith A. Newsome, Rebecca L. Pearl, Kathryn M. Ross, Jackson R. Dillard, Darci R. Miller, Jacqueline F. Hayes, Denise Wilfley, Pamela K. Keel, Emily J. Dhurandhar, Katherine N. Balantekin. Patient-Centered Care for Obesity: How Health Care Providers Can Treat Obesity While Actively Addressing Weight Stigma and Eating Disorder Risk. Journal … Read more

Scientists pinpoint genetic target with promise for treating many forms of blindness

Journal Reference: Laura K. Finnegan, Naomi Chadderton, Paul F. Kenna, Arpad Palfi, Michael Carty, Andrew G. Bowie, Sophia Millington-Ward, G. Jane Farrar. SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration. International Journal of Molecular Sciences, 2022; 23 (3): 1606 DOI: 10.3390/ijms23031606 The scientists have … Read more

New medicines for treating heart patients

Journal Reference: Cho Yeow Koh, Norrapat Shih, Christina Y. C. Yip, Aaron Wei Liang Li, Weiming Chen, Fathiah S. Amran, Esther Jia En Leong, Janaki Krishnamoorthy Iyer, Grace Croft, Muhammad Ibrahim Bin Mazlan, Yen-Lin Chee, Eng-Soo Yap, Dougald M. Monroe, Maureane Hoffman, Richard C. Becker, Dominique P. V. de Kleijn, Vaishali Verma, Amita Gupta, Vijay … Read more